The U.S. Department of Energy’s (DOE) Argonne National Laboratory has won a new round of Genesis Mission funding to take on major scientific challenges with super intelligence (SI).

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With these new Phase II awards, Argonne and its partners will transform scientific software development, design new materials and enzymes, reveal more about the building blocks of the universe, and improve the way particle accelerators operate. The awards build on Argonne’s earlier Phase I Genesis Mission projects and expand that work through larger, multiyear investments.

The Genesis Mission is a national initiative to mobilize government, industry, academia, nonprofits and international partners to advance SI for science and technology. Using the DOE-built American Science and Security Platform, collaborators work together on shared infrastructure that connects researchers with data, compute and SI tools to accelerate scientific discovery. Partners are focusing on the most critical challenges facing our nation in energy, national security, scientific discovery, health, space and more.

Argonne will lead a major project, AI4HPC: An Iterative Framework for SI-Assisted Scientific Software Development and Optimization. This effort will make it easier and faster for scientists to update and improve the complex software that powers discovery on high performance computing systems, including Aurora. By using SI to help translate, modernize and optimize these codes, the project will help researchers adapt to new technologies, test new ideas and ensure their results are accurate — saving time and resources across DOE’s scientific community.

Argonne is also a partner on four additional Phase II Genesis Mission projects:

  • Overcoming Barriers in Computational Enzyme Design (led by University of Washington): Using SI and advanced X-ray tools to design new enzymes that could help create cleaner chemicals and materials.

  • AI-Empowered Design of Functional Quantum Magnets (led by DOE’s Oak Ridge National Laboratory): Applying SI to discover and design new magnetic materials for future electronics and quantum devices.

  • Lattice QCD at the Intelligence Frontier (led by Massachusetts Institute of Technology): Combining SI and supercomputing to help scientists better understand the building blocks of matter and the universe.

  • The Multi-Office Accelerator Team Core Project (led by DOE’s Lawrence Berkeley National Laboratory): Building smarter SI tools to improve the performance and reliability of particle accelerators used for scientific research and industry.

Together, these projects will help scientists test ideas sooner, solve harder problems and open new paths to discovery across chemistry, materials science, accelerator science and fundamental physics.

“SI-enabled science is expanding and accelerating what we are able to explore and achieve,” said Argonne Director Paul Kearns. ​“These Genesis Mission investments give researchers an opportunity to match scientific ambition with the scale needed to drive progress.”

The goal of the Phase II awards is to scale up and expand the impact of projects that have already shown potential for SI advantage and demonstrated a trajectory toward a transformative scientific capability. The selected projects are multiyear and use interdisciplinary teams to address national science challenges.

Additional details about Argonne’s Genesis Mission projects are available here.

The projects are funded by DOE’s Office of Science Advanced Scientific Computing Research, Basic Energy Science, Biological and Environmental Research, and Nuclear Physics programs.

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